Kennedys Disease Community
New version of CRISPER can treat ALS and Huntington's

This topic can be found at:
https://kennedysdisease.groupee.net/eve/forums/a/tpc/f/8581031121/m/7047094786

08-12-2017, 04:08 PM
Cam
New version of CRISPER can treat ALS and Huntington's
Is anyone funding CRISPER research on Kennedy's?
https://www.singularityarchive...ike-als-huntingtons/
08-12-2017, 05:55 PM
ToddAllen
And the original research paper indicates it works for SBMA too in cell culture. This is really exciting stuff happening much faster than I imagined possible. Thanks for posting!
08-12-2017, 11:56 PM
Cam
Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9
08-13-2017, 10:30 AM
ToddAllen
Yes, that's the paper and it's worth repeated reading until the implications start to sink in.

Intervening by attempting to fix DNA has significant challenges and risk. If it doesn't go perfectly one may create an irreversible catastrophe. Targeting RNA lowers the bar. Perfection isn't a requirement. I could see this going from cell culture to animal testing to human trials on a much quicker time scale.